Moderna shares fell 26% intraday and closed down 18% after Phase III data for its mRNA cancer vaccine leaked two days before scheduled presentation.
Moderna's Phase III showed 42% relative risk reduction, below the 49% from Phase II, prompting investor disappointment over weaker results.
Hosts mock influencer Shane Stouffer, who flipped his Moderna position from calls to puts hours before the plunge, losing nearly $200,000.
Moderna Cancer Vaccine Data Leaks Early and Shares Tumble
Funding and deals
Whop. Digital commerce and creator platform Whop raised $205m with Sequoia and Shopify Ventures, after growing 300 percent following its first year.
Guest interviews
Kyle Schiller, CEO of Marathon Fusion. Schiller argues fusion is bottlenecked by fuel-cycle and industrial technologies far more than by core plasma physics. Marathon says it is roughly five orders of magnitude from the power density record and plans to double power density monthly. The company also targets gold and medical isotopes, and has 30 people.
Thomas Wright, CEO and principal broker of Summit Sotheby's International Realty. Wright says luxury real estate has surged, led by the top 1 percent, and cites a $54tn figure from the Sotheby's Luxury Outlook report. He traces Utah's growth to the 2002 Winter Olympics and says the state has consistently ranked first in business opportunity. He calls AI-enhanced listing photos a step too far because they misrepresent the property.
Steven Schwartz, co-founder and CEO of Whop. Schwartz says about 10,000 people each day try to create businesses on Whop, including a Kansas car cleaner earning $150 a week. AI business training is the fastest-growing category.
News
Moderna cancer vaccine data leaks, shares fall 18 percent. Phase III data for the mRNA vaccine, given with Merck's Keytruda, leaked before its presentation and showed a 42 percent relative risk reduction versus 49 percent in Phase II. Shares closed down 18 percent.
Quest Diagnostics discloses breach exposing patient data. Unauthorized access to its Quantum Lab service manager exposed some patient data. Quest runs tests for cancer and HIV, so the exposed data may be very private.
Data center boom drives surge in gray paint demand. PPG's vice president says he has never seen a boom as big as data centers, and Sherwin Williams said protective and marine sales rose by a mid-teens percentage from a year earlier.
Ben Lamm's firm will engineer military dogs. The company is coming out of stealth to genetically engineer dogs for military and law enforcement, with units Lamm says could weigh eight times more and resist bullets 100 times better.
Hosts weigh AI labs' duty to patch flaws. John Coogan asks whether labs should have a duty to patch vulnerabilities they find. Jake Vintz says he has heard OpenAI people describe unfixable hardware bugs that AI models could exploit.
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